Immunohistochemistry Kits and Reagents
ABclonal Technology IGF2BP1/IMP1 Rabbit mAb
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family The protein encoded by this gene contains four K homology domains and two RNA recognition motifs It functions by binding to the mRNAs of certain genes including insulin-like growth factor 2 beta-actin and beta-transducin repeat-containing protein and regulating their translation Two transcript variants encoding different isoforms have been found for this gene
Cayman Chemical DDR1-IN-1hydrate 5mg
A selective DDR1 inhibitor (IC50 = 105 nM; EC50 = 87 nM; inhibits colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor, GSK2126458
MilliporeSigma MILLIPLEX MAP Human High Sensitivity T Cell Panel Premixed 13-plex - Immunology Multiplex Assay, 96 wells
Simultaneous analyze low levels of cytokine and chemokine biomarker with the High Sensitivity Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.
Revvity Health Sciences Inc AlphaLISA Human CXCL11 Detection Kit, 5,000 Assay Points
AlphaLISA Human CXCL11 Detection Kit, 5,000 Assay Points
ABclonal Technology RANKL Rabbit pAb
This gene encodes a member of the TNF cytokine family, acting as a ligand for osteoprotegerin and playing a key role in osteoclast differentiation and activation. It also functions as a dendritic cell survival factor and regulates T cell-dependent immune responses. T cell activation induces expression of this gene, promoting osteoclastogenesis and bone loss. The protein activates the antiapoptotic kinase AKT/PKB via a signaling complex with SRC kinase and TRAF6, suggesting a role in apoptosis regulation. Disruption of the related gene in mice causes severe osteopetrosis, lack of osteoclasts, and defects in T and B lymphocyte differentiation, as well as failure to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been identified.
ABclonal Technology Phospho-SMO-S616 Rabbit pAb
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
ABclonal Technology SLC22A7 Rabbit pAb
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.
Cell Signaling Technology PathScanR Phospho-DDR1 panTyr Sandwich ELISA Kit 20 Kit
PathScanR Phospho-DDR1 panTyr Sandwich ELISA Kit 20 Kit
ABclonal Technology NDUFA4L2 Rabbit pAb
Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex IV.
Cayman Chemical p38 MAPK InhIbItr VIII 10mg
An inhibitor of p38α (IC50 = 39 nM) and p38β MAP kinases with 82 and 93% inhibition, respectively, in a kinase assay (1 µM); selective for p38α and 38β, lacking activity at p38γ, p38δ, ERK1/2, and JNK1 at 1 µM; inhibits IL-1β, TNF-α, IL-6, IL-8, and IL-10, but not IFN-γ release from human peripheral blood mononuclear cells (IC50s = 30, 5, 17, 4, 10, and >1,000 nM, respectively); decreases EAr swelling in mouse models of allergic and chronic irritative contact dermatitis (0.5 mg/ear, topical)
Revvity Health Sciences Inc AlphaLISA Human MMP13 Detection Kit, 500 Assay Points
AlphaLISA Human MMP13 Detection Kit, 500 Assay Points